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10.1016/j.bioeng.2006.05.020 39 FyfeP

Effective pharmacological therapies include statins for the treatment of dyslipidemia, antiplatelet medicines for the reduction of prothrombotic risk, and insulin sensitizers for the prevention of diabetes

Direct human clinical evidence remains insufficient

Enhances the production of the neurotransmitter acetylcholine, supporting brain function

elegans (Tanizawa et al., 2006) has indeed shown that these enzymes play an important role in regulation of synaptic function in vivo , although this appears to be mediated by enhancing rather than suppressing synaptic transmission

Berberine promotes mitochondrial biogenesis and increases energy production in an AMP-activated protein kinase (AMPK)-dependent manner