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Coskun 2022 mmc3 Table 3 + mmc1 Table S8 Phase 1 single-ascending-dose study (NCT03841630, n=45, conducted in Singapore)

[8] Both drugs can cause the usual side effects like nausea, vomiting, diarrhea, constipation, and fatigue

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The mechanisms underlying T4's efficacy in this condition likely involve compensation for reduced endogenous growth factor availability, direct stimulation of epithelial cell migration and proliferation, and anti-inflammatory effects that create a more favorable environment for healing

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