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Trends Cardiovasc Med (2008) 18(1):614

Based on structural and functional differences, the family is divided into two groups: Rel proteins (RelA, RelB, and c-Rel), which possess transcription activation domains (TADs), and NF-B1 and NF-B2, which lack TADs in their mature forms (p50 and p52) and require co-activators such as Bcl-3 for transcriptional activity [6]

It is widely recognized that eicosanoids, which are generated through the COX-2 and 5-LOX pathways, play a role in the advancement of colon cancer

Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin from Helicobacter pylori

Many find adequate results at 10 mg or 12.5 mg with fewer side effects

Possible side effects: Rare allergic reactions